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<p>Despite major advances in healthcare over the past century, the successful treatment of cancer has remained a significant challenge, and cancers are the second leading cause of death worldwide behind cardiovascular disease. Early detection and survival are important issues to control cancer. The development of quantitative methods and computer technology has facilitated the formation of new models in medical and biological sciences. The application of mathematical modelling in solving many real-world problems in medicine and biology has yielded fruitful results. In spite of advancements in instrumentations technology and biomedical equipment, it is not always possible to perform experiments in medicine and biology for various reasons. Thus, mathematical modelling and simulation are viewed as viable alternatives in such situations, and are discussed in this book.The conventional diagnostic techniques of cancer are not always effective as they rely on the physical and morphological appearance of the tumour. Early stage prediction and diagnosis is very difficult with conventional techniques. It is well known that cancers are involved in genome level changes. As of now, the prognosis of various types of cancer depends upon findings related to the data generated through different experiments. Several machine learning techniques exist in analysing the data of expressed genes; however, the recent results related with deep learning algorithms are more accurate and accommodative, as they are effective in selecting and classifying informative genes. This book explores the probabilistic computational deep learning model for cancer classification and prediction.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p><em>The Energy Reader</em> takes an unflinching look at the environmental devastation created by our thirst for energy-including supposedly clean” renewable sources. From oil spills, nuclear accidents, and mountaintop-removal coal mining to oversized wind farms and desert-destroying solar power plants, virtually every region of the globe is now experiencing the consequences of out-of-control energy development. Essentially no place is sacred, no landscape safe from the relentless search for energy resources to continue powering a culture based on perpetual growth. Precious wildlands, fragile ecosystems, even our own communities and children’s health are at risk.</p> <p>Featuring essays by more than thirty of the most brilliant minds in the fields of energy, society, and ecology, <em>The Energy Reader</em> lifts the veil on the harsh realities of our pursuit of energy at any price, revealing the true costs, benefits, and limitations of all our energy options. Contributors include Wes Jackson, Bill McKibben, Sandra B. Lubarsky, Richard Heinberg, Philip Cafaro, Wendell Berry, Juan Pablo Orrego. Collectively, they offer a wake-up call about the future of energy and what each of us can do to change course.</p> <p>Ultimately, the book offers not only a deep critique of the current system that is toxic to nature and people, but also a hopeful vision for a future energy economy-in which resilience, health, beauty, biodiversity, and durability, not incessant growth, are the organizing principles.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>This book constitutes the thoroughly refereed proceedings of the First Big Social Data and Urban Computing Workshop, BiDU 2018, held in Rio de Janeiro, Brazil, in August 2018.</p> <p>The 11 full papers presented were carefully reviewed and selected from 40 submissions. The papers are organized in topical sections on urban mobility, urban sensing, contemporary social problems, collaboration and crowdsourcing.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。
<p>Written for civil, structural and geotechnical engineers, this book presents the latest research and practical experience in the design of high-arch dams in seismically active regions, from an author team that is highly active and experienced in the design, development and construction of 300m high arch dams.</p> <p>The book covers the entire subject of dam design for seismic regions, including seismic input mechanisms and modeling, non-linear analysis techniques for dam structure and foundations, concrete material properties, and simulation techniques for dam design. Of particular value are the real-world experimental data and design case studies that enhance the book and ensure that readers can apply the theoretical content to their own projects.</p> <ul> <li>Break through the conventional concepts in civil engineering discipline and focus on applying new techniques from other subject fields to seismic safety on high-arch dam design in an innovative way</li> <li>Shows how to model and evaluate seismic safety of dams using seismic input, dam response and dynamic resistance</li> <li>Summarizes the methodology and approaches applied to high-arch dam design and construction in China, demonstrates the selection of site-specific seismic input parameters, and enables the reader to apply this to their own specific design challenge</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p><strong>Friendly advice on leveraging the power of the new Nexus 7 Google tablet!</strong></p> <p>The arrival of the new Nexus 7 Google tablet is eagerly awaited, thanks to its cutting-edge software, top-notch hardware, unprecedented abilities, and nine-hour battery life. This easy-to-understand, engaging guide covers everything you need to know about this amazing Android tablet. Bestselling Dummies author Dan Gookin uses his friendly writing style to deliver clear instructions for setting up, navigating, and using the device. You'll learn to use all your favorite Google applications that come loaded on the device, personalize it, and much more.</p> <ul> <li>Walks you through the touchscreen, wireless access, and software updates</li> <li>Demonstrates how to download, shop for, and fill your Nexus 7 with movies, e-books, games, and music</li> <li>Helps you keep on top of your schedule and appointments and pursue your interests and hobbies with the latest apps and websites</li> <li>Offers guidance on using your device to navigate from here to there and stay connected with friends and family while you're away</li> </ul> <p><em>Nexus 7 For Dummies</em> is an essential companion to your other new companion: the Nexus 7!</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p><em>European Social Policy and Social Work</em> explores shifts in international social policies and how they affect national trends and thus the context for social work practice.</p> <p>The book discusses international and national social work strategies and practice and investigates the responsibilities for social welfare held by the state, the market and civil society. Hans van Ewijk then elaborates a new concept of citizenship-based social work which supports and encourages self-responsibility, social responsibility and the implementation of social rights. The main themes covered are:</p> <ul> <li>international social policy and social work</li> <li>from welfare to workfare</li> <li>citizenship</li> <li>essentials of citizenship based social work</li> <li>community policy and community work</li> <li>social work and alternative areas of activity such as youth care and social care.</li> </ul> <p>Integrating different roots and social professions in an overarching new concept, this book particularly looks at European Union countries. Hans van Ewijk examines debates regarding social work as an internationally recognised profession and science.</p> <p>This book is suitable for social work students, academics and professionals with an interest in social policy and international social work.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
ARTIFICIAL INTELLIGENCE IN EDU Wei Wang Guangming Wang Xiaoming Ding SPRINGER NATURE2021 Hardcover 2021 English ISBN:9789811665011 洋書 Computers & Science(コンピューター&科学) Computers
RNA LIFES INDISPENSABLE MOLECU James Darnell COLD SPRING HARBOR LABORATORY2011 Hardcover English ISBN:9781936113194 洋書 Computers & Science(コンピューター&科学) Science
<p>There are two distinct philosophies of medicine throughout the world. Simply put, one philosophy considers the symptom to be the disease, and the other considers the symptoms important but not the disease.<br /> Any philosophy that considers the symptom to be the disease will inevitably give rise to a system or systems of medicine that are aimed at the effective removal of symptoms, and this approach is the dominant system throughout the world today.<br /> We are all very familiar with the system in one form or another, that holds the symptom to be the disease, it is generally referred to as medical science, or conventional medicine. We experience it as practiced by general medical practitioners (doctors), specialists and surgeons, and is delivered through surgeries, health centres and hospitals.<br /> Most of these practitioners would argue that they are not delivering a service based on such a simplistic principle, and would point at the great advances in understanding the nature of disease agents and the sophisticated medicines now at their disposal to treat them. However a brief glance at the categories of medicines and surgical procedures will reveal that they are generally aimed at removal or suppression of symptoms. We are all familiar with Pain killers, anti inflammatory drugs, broncho- dilators, diuretics, anti biotics etc; and it is undoubtedly true that in most cases these drugs will perform their specific task effectively.<br /> Ever since the intellect of man has developed sufficient capacity, it has sought to alleviate pain and suffering, and in most societies both primitive (so called) and the technologically advanced, have discovered, historically, plants and minerals, to use as medicines, and in modern developed societies, these primitive medicines have been superseded in many cases by synthetically produced medicines, designed to do the same job more effectively.<br /> It is perfectly understandable that a suffering individual would want to be free of the symptoms as quickly as possible, and barring any unpleasant ‘reaction or after effect’ to the treatment, will consider the job effectively complete, and think no more about it.<br /> As medical practice has evolved with detailed observation of cases over time and effective record keeping has shown that the taking of medicines to treat symptomatology rather than address the causes of those symptoms, can lead to more serious conditions with new symptomatology, requiring the prescribing of yet more powerful medication to subdue the new symptom picture, or surgical intervention in some cases.<br /> Throughout recent history there have been voices pointing out the possible short comings of this rather superficial approach to treating disease and the negative effects of the powerful medicines and drugs employed.<br /> Today we have an explosion (hundreds, maybe thousands) of so called natural or alternative systems of medicine, however with closer examination of the methods and medicines used we find that the materials may be an alternative to regular pharmaceutical medicines but the methodology and philosophy are based on exactly the same principle i.e.: the symptom is the disease. With the same drawbacks if the medicine is effective in merely removing or suppressing the symptom.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>The remarkable story of a "talking" chimp, a leading scientist, and the profound insights they have uncovered about our species</p> <p>He has been featured in cover stories in Time, Newsweek, and National Geographic, and has been the subject of a "NOVA" documentary. He is directly responsible for discoveries that have forced the scientific community to recast its thinking about the nature of the mind and the origins of language. He is Kanzi, an extraordinary bonobo chimpanzee who has overturned the idea that symbolic language is unique to our species. This is the moving story of how Kanzi learned to converse with humans and the profound lessons he has taught us about our animal cousins, and ourselves.</p> <p>" . . . The underlying thesis is informative and well argued . . . Savage-Rumbaugh's results are impressive." ー The Washington Post</p> <p>"This popular, absorbing, and controversial account is recommended." ー Library Journal</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>The first three editions of <em>Fungi and Food Spoilage</em> established, then consolidated, a reputation as the leading book on foodborne fungi. It details media and methods for isolation and identification, descriptions of species, and information on their physiology, ecology and mycotoxin formation. It is an invaluable reference for food microbiologists investigating fungal food spoilage problems, both in field crops and processed foods, and the likelihood of mycotoxin production in either.</p> <p>The Fourth Edition incorporates major differences from the Third: multiple changes in nomenclature due to changes in the International Code of Nomenclature for algae, fungi and plants; many taxonomic changes due to improvements in, and more widespread application of, molecular methods in taxonomy; the introduction of colour colony photographs where appropriate; and a new chapter on mycotoxins.</p> <p>The introductory chapters of the book deal with the ecology of food spoilage, and provide an overview of how food processing, packaging and storage parameters influence fungal growth. A subsequent chapter overviews the fundamentals of naming and classifying fungi. Morphological methods and media suitable for low cost and effective isolation, enumeration and identification of foodborne fungi are provided, together with many more specialised media and techniques.</p> <p>The major part of the book provides keys, descriptions and illustrations of all yeasts and filamentous fungi commonly encountered in foods. Other known characteristics of the species, including physiology and ecology are included. Chapters on the types and species of fungi likely to be found in fresh, harvested and variously processed foods are followed by a new chapter on mycotoxins, both major and minor, their sources, both fungal and food, and their implications for human health.</p> <p>The broad and practical nature of the coverage will appeal to microbiologists, mycologists and biotechnologists in the food industry, as well scientists in academic, research and public health institutions.</p> <p>Drs Pitt and Hocking worked for CSIRO Food for more than 100 years combined. Both are now retired from CSIRO: Dr Pitt continues to work part time with Microbial Screening Technologies, a biodiscovery company.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>This volume highlights the latest advances and innovations in the field of soil mechanics and geotechnical engineering, as presented by leading international researchers and engineers at the 5th International Conference on New Developments in Soil Mechanics and Geotechnical Engineering (ZM), held in Nicosia, Northern Cyprus on June 30-July 2, 2022. It covers a diverse range of topics such as soil properties and characterization; shallow and deep foundations; soil improvement; excavations, support systems, earth-retaining structures and underground systems; earthquake geotechnical engineering; stability of slopes and landslides; fills and embankments; environmental preservation, water and energy; modelling and analyses in geotechnical engineering. The contributions, which were selected by means of a rigorous international peer-review process, present a wealth of exciting ideas that will open novel research directions and foster multidisciplinary collaboration among different specialists.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>Plague was one of the enduring facts of everyday life on the European continent, from earliest antiquity through the first decades of the eighteenth century. It represents one of the most important influences on the development of Europe’s society and culture. In order to understand the changing circumstances of the political, economic, ecclesiastical, artistic, and social history of that continent, it is important to understand epidemic disease and society’s response to it.</p> <p>To date, the largest portion of scholarship about plague has focused on its political, economic, demographic, and medical aspects. This interdisciplinary volume offers greater coverage of the religious and the psychological dimensions of plague and of European society’s response to it through many centuries and over a wide geographical terrain, including Byzantium. This research draws extensively upon a wealth of primary sources, both printed and painted, and includes ample bibliographical reference to the most important secondary sources, providing much new insight into how generations of Europeans responded to this dread disease.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p><strong>Ten minibooks in one! The perfect reference for beginning web builders</strong></p> <p>This hefty, 800+ page book is your start-to-finish roadmap for building a web site for personal or professional use. Even if you're completely new to the process, this book is packed with everything you need to know to build an attractive, usable, and working site. In addition to being a thorough reference on the basics, this updated new edition also covers the very latest trends and tools, such as HTML5, mobile site planning for smartphones and tablets, connecting with social media, and more.</p> <ul> <li>Packs ten minibooks into one hefty reference: Preparation, Site Design, Site Construction, Web Graphics, Multimedia, Interactive Elements, Form Management, Social Media Integration, Site Management, and Case Studies</li> <li>Covers the newest trends and tools, including HTML5, the new Adobe Create Suite, and connecting with social media</li> <li>Offers in-depth reviews and case studies of existing sites created for a variety of purposes and audiences, such as blog sites and non-profit sites</li> <li>Walks you through essential technologies, including Dreamweaver, HTML, CSS, JavaScript, PHP, and more</li> </ul> <p>Plan, build, and maintain a site that does exactly what you need, with <em>Building Web Sites All-In-One For Dummies, 3rd Edition</em>.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>Dieses Buch f?hrt Anf?nger und Fortgeschrittene Schritt f?r Schritt mit vielen Praxisbeispielen in die f?hrende Programmiersprache f?r Messtechnik "LabVIEW" ein. Der erste Teil des Buchs erkl?rt ausf?hrlich und umfassend die Programmiersprache LabVIEW. Die Kapitel schlie?en jeweils mit instruktiven Beispielen. Aufgrund des Umfangs von LabVIEW, das mehr als tausend ausprogrammierte Algorithmen hat, beschr?nkt sich das Buch auf die wichtigsten Algorithmen und Sprachelemente, sodass Sie sich nicht mit unn?tigem Ballast befassen m?ssen. Der zweite Teil des Buchs zeigt, wie leicht man mit LabVIEW technische, physikalische und mathematische Probleme unterschiedlichster Bereiche l?sen kann. Die Experimente sind mit einfacher, oft bereits vorhandener Ausr?stung m?glich. Praxis-relevante Themen wie Messdatenerfassung, serielle Schnittstelle und Soundkartenprogrammierung werden ausf?hrlich besprochen. Anhand von einfach durchzuf?hrenden Experimenten wie dem Messen eines EKGs, der Ansteuerung eines Schrittmotors oder dem Bau eines 3-D-Scanners werden wichtige Kenntnisse f?r die Realisierung eigener Projekte vermittelt. Sie k?nnen ohne gro?e Investition durchgef?hrt werden und sind hinsichtlich der Durchf?hrung und Mathematik vollst?ndig beschrieben und erprobt. Die Experimente sind auch als Labor?bung an Hochschulen sowie f?r Auszubildende, Ingenieure und Autodidakten, die mit LabVIEW arbeiten, geeignet. Praktische Experimente *EKG *Schrittmotoransteuerung *Wechselrichter - Drehstrom aus dem Laptop *Dehnungsmessstreifen *Terminalprogramm *Signalverarbeitung in der Praxis *Akustisches GPS *Bildverarbeitung mit zweidimensionaler Fourier-Transformation *Temperaturverteilung in einem Ring *3-D-Scanner mit Laptop und Beamer *Praktische Bildverarbeitung *und viele mehr</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>In spring this year it will be 23 years since I began to study rotation technique as applied to radiology. In applying this technique to roentgenography the name Rotation Radiography was adopted publicly in 1946. Since then this study has revealed that the technique is valuable not only in diagnosis but also in radiotherapy, and the name Conformation Radiotherapy was publicly an nounced in 1960. Through these studies it became clear that it is possible to show the axial transverse cross section of the human body roentgenographically, which could be of great value medically, but it was realized that no detailed roentgenograms of the axial transverse cross section covering the whole of the normal human adult have been published so far. To prepare an atlas was therefore considered basic for the practical application of this method, since without it further developments of this type of roentgenography cannot be expected. Conse quently it was decided first to prepare the atlas. In addition, the clinical application of this method to the diagnostic and therapeutic field was described with brief notes on the essential features of the method.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>Magnetic resonance imaging has become an increasingly beneficial tool for the radiologic evaluation of complex spine diseases. However, due to the many variables implicit in MR imaging technique, considerable experience and expertise are necessary to diagnose with confidence.</p> <p>This book provides a comprehensive and practical overview of the field, and gives you the information to competently utilize MRI for the diagnosis of diseases of the spine and spinal cord.</p> <ul> <li>More than 1,300 high-quality images help you recognize and distinguish normal findings from pathologic spinal disorders and common MR artifacts</li> <li>Systematic tables of indications and differential diagnoses summarize each disorder and help you in planning treatment strategies</li> <li>Problem-solving tips and tricks provide details on various imaging techniques, as well as the advantages and disadvantages of different MRI sequences</li> <li>Concise chapter summaries provide quick and easy access to the most current MR imaging information</li> </ul> <p>Of great interest to radiologists, neuroradiologists, trauma surgeons, orthopedic surgeons, and neurosurgeons, this extensively illustrated work is an essential diagnostic reference for evaluating spinal disorders.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p><strong>Featured</strong> <strong>With</strong>:</p> <p>● PANDAS</p> <p>● PYTHON LIBRARY</p> <p>● DATABASE PROGRAMMING</p> <p>● GUI PROGRAMMING</p> <p>● DIY APPLICATIONS</p> <p>● FOR ENGINEERING STUDENTS</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p>La question de la prescription excessive de m?dicaments psychiatriques en France comme en Belgique revient de plus en plus fr?quemment sur la place publique. Dans ce contexte, cet ouvrage apporte une information sur chaque classe de m?dicaments ? la fois tr?s compl?te et ind?pendante de celle fournie par les firmes pharmaceutiques. Il replace la psychopharmacologie dans sa dimension historique, fait le point sur la r?alit? des connaissances actuelles en mati?re de psychotropes : leurs effets r?els et leurs risques potentiels dans la pratique clinique. Certaines alternatives aux traitements m?dicamenteux sont ?galement abord?es. Adapt? au lectorat francophone par une mise en concordance de la d?nomination commune internationale des m?dicaments avec les noms de marques vendus en France, en Suisse, en Belgique et au Canada, cette traduction tient ?galement compte des diff?rences de pratique entre les mondes francophone et anglo-saxon. Il est destin? ? la fois aux prescripteurs et aux professionnels qui travaillent avec les personnes prenant des m?dicaments psychiatriques.</p> <p>Cet ouvrage apporte une information sur chaque classe de m?dicaments tr?s compl?te et ind?pendante de celle fournie par les firmes pharmaceutiques. Il replace la psychopharmacologie dans sa dimension historique, fait le point sur la r?alit? des connaissances actuelles en mati?re de psychotropes : leurs effets r?els et leurs risques potentiels dans la pratique clinique. Il est destin? ? la fois aux prescripteurs et aux professionnels qui travaillent avec les personnes prenant des m?dicaments psychiatriques.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p><strong>Using TRILL, FabricPath, and VXLAN</strong></p> <p>Designing Massively Scalable Data Centers with Overlays</p> <p>TRILL, FabricPath, and VXLAN overlays help you distribute data traffic far more effectively, dramatically improving utilization in even the largest data center networks. Using TRILL, FabricPath, and VXLAN is the first practical and comprehensive guide to planning and establishing these high-efficiency overlay networks. The authors begin by reviewing today’s fast-growing data center requirements, and making a strong case for overlays in the Massive Scale Data Center (MSDC). Next, they introduce each leading technology option, including FabricPath, TRILL, LISP, VXLAN, NVGRE, OTV, and Shortest Path Bridging (SPB). They also present a chapter-length introduction to IS-IS, focusing on details relevant to the control of FabricPath and TRILL networks. Building on this foundation, they offer in-depth coverage of FabricPath: its advantages, architecture, forwarding, configuration, verification, and benefits in Layer-2 networks. Through examples, they explain TRILL’s architecture, functionality, and forwarding behavior, focusing especially on data flow. They also fully address VXLAN as a solution for realizing IP-based data center fabrics, including multi-tenant cloud applications.</p> <p>Using TRILL, FabricPath, and VXLAN provides detailed strategies and methodologies for FabricPath, TRILL, and VXLAN deployment and migration, as well as best practices for management and troubleshooting. It also presents three detailed implementation scenarios, each reflecting realistic data center challenges. In particular, the authors show how to integrate multiple overlay technologies into a single end-to-end solution that offers exceptional flexibility, agility, and availability.</p> <p><strong>Sanjay K. Hooda</strong> is principal engineer in Catalyst switching software engineering at Cisco. He has more than 15 years of network design and implementation experience in large enterprise environments, and has participated in IETF standards activities. His interests include wireless, multicast, TRILL, FabricPath, High Availability, ISSU, and IPv6. He is co-author of IPv6 for Enterprise Networks.</p> <p><strong>Shyam Kapadia</strong>, Technical Leader at Cisco’s Data Center Group (DCG), was an integral part of the team that delivered the next-generation Catalyst 6500 Sup 2T (2 Terabyte) platform. Since then, he has focused on developing new solutions for data center environments. He holds a Ph.D. in computer science from USC, where his research encompassed wired, wireless, ad hoc, vehicular, and sensor networks.</p> <p><strong>Padmanabhan Krishnan</strong> has more than 12 years of experience in networking and telecommunications, including 7 at Cisco. His recent experience has included providing data path solutions for TRILL in the Catalyst 6500 Sup 2T Platform using FPGA, as well as design and development of platform core infrastructure and L2 features.</p> <p>n Discover how overlays can address data center network problems ranging from scalability to rapid provisioning</p> <p>n Examine popular data center overlay examples</p> <p>n Learn about extensions to IS-IS for TRILL and FabricPath</p> <p>n Use FabricPath, TRILL, and VXLAN to simplify configuration, improve performance and availability, optimize efficiency, and limit table size</p> <p>n Learn about FabricPath control and data plane architecture details</p> <p>n Review example FabricPath configurations on Cisco Nexus 7000/6000/5000 switches</p> <p>n Understand TRILL concepts and architecture, including overlay header, control and data plane, and MAC address learning</p> <p>n Learn about VXLAN architecture details and packet forwarding</p> <p>n Review example VXLAN configurations on a Cisco Nexus 1000V distributed virtual switch</p> <p>n Implement TRILL/FabricPath networks with VXLAN to virtualized servers in an intra-data center environment</p> <p>n Connect multiple traditional data centers using an OTV overlay as a Layer 2 extension</p> <p>n Use OTV overlays to connect sites running FabricPath, TRILL, or both</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
<p><em>Genome Stability: From Virus to Human Application, Second Edition</em>, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging.</p> <p>This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability.</p> <ul> <li>A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects</li> <li>Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability</li> <li>Contains applications of genome instability research and outcomes for human disease</li> <li>Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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